Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 3/20 | 0.31 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7986119 | 0.96 | LMNA (0.58) | LMNACYP2C19HIF1AEGFRSRC | |
| Ioversol SCHEMBL9745016 | 0.90 | LMNA (0.64) | LMNACYP2C19HIF1AEGFRSRC | |
| Ioversol SCHEMBL24711 | 0.90 | LMNA (0.64) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9009203 | 0.89 | CYP2C19 (0.73) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL7795950 | 0.88 | LMNA (0.59) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL5033214 | 0.88 | LMNA (0.61) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8438095 | 0.88 | LMNA (0.64) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9736495 | 0.88 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9196493 | 0.87 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9234116 | 0.87 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0083964-B1 | COMPOUNDS SUITABLE FOR X-RAY VISUALISATION METHODS | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1986-04-16 | — | — | EP | claimed |
| US-4396598-A | Triiodoisophthalamide X-ray contrast agent | MALLINCKRODT, INC. (US) | 1983-08-02 | — | — | US | claimed |
| EP-0083964-A1 | Compounds suitable for X-ray visualisation methods | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1983-07-20 | — | — | EP | claimed |
| US-6596904-B1 | Process for producing ioversol | MALLINC KRODT INC | 2003-07-22 | — | — | US | disclosed |
| EP-0839056-B1 | PROCESS FOR PRODUCING IOVERSOL | MALLINCKRODT INC (US) | 2003-05-07 | — | — | EP | disclosed |
| EP-0886634-B1 | PROCESS FOR PRODUCING IOVERSOL | MALLINCKRODT INC (US) | 2002-04-24 | — | — | EP | disclosed |
| US-5648536-A | Process for producing ioversol | LAFAYETTE PHARMACEUTICALS LLC | 1997-07-15 | — | — | US | disclosed |
| EP-0513063-B1 | PROCESS FOR PRODUCTION OF IOVERSOL | MALLINCKRODT INC (US) | 1995-05-17 | — | — | EP | disclosed |
| EP-0619744-A4 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS. | MALLINCKRODT MEDICAL INC (US) | 1995-02-08 | — | — | EP | disclosed |
| US-5371278-A | Increasing reaction solution concentration and temperature | MALLINCKRODT MEDICAL PMC (US) | 1994-12-06 | — | — | US | disclosed |
| EP-0619744-A1 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT MEDICAL, INC. (US) | 1994-10-19 | — | — | EP | disclosed |
| WO-1991011431-A1 | PROCESS FOR PRODUCTION OF IOVERSOL | MALLINCKRODT, INC. (US) | 1991-08-08 | — | — | WO | disclosed |
| WO-1991011431-A1 | PROCESS FOR PRODUCTION OF IOVERSOL | MALLINCKRODT, INC. (US) | 1991-08-08 | — | — | WO | disclosed |
| WO-1991009007-A2 | NONIONIC X-RAY CONTRAST AGENTS, COMPOSITIONS AND METHODS | MALLINCKRODT, INC. (US) | 1991-06-27 | — | — | WO | disclosed |
| US-4997983-A | Process for production of ioversol | MALLINCKRODT, INC. (US) | 1991-03-05 | — | — | US | disclosed |
| EP-0083964-B1 | COMPOUNDS SUITABLE FOR X-RAY VISUALISATION METHODS | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1986-04-16 | — | — | EP | disclosed |
| US-4396598-A | Triiodoisophthalamide X-ray contrast agent | MALLINCKRODT, INC. (US) | 1983-08-02 | — | — | US | disclosed |
| US-4396598-A | Triiodoisophthalamide X-ray contrast agent | MALLINCKRODT, INC. (US) | 1983-08-02 | — | — | US | disclosed |
| EP-0083964-A1 | Compounds suitable for X-ray visualisation methods | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1983-07-20 | — | — | EP | disclosed |
| EP-0083964-A1 | Compounds suitable for X-ray visualisation methods | Mallinckrodt, Inc. (a Delaware corporation) (US) | 1983-07-20 | — | — | EP | disclosed |