Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.30 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.30 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ioversol SCHEMBL9745016 | 0.95 | LMNA (0.64) | LMNACYP2C19HIF1AEGFRSRC | |
| Ioversol SCHEMBL24711 | 0.95 | LMNA (0.64) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9736495 | 0.93 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL7986119 | 0.92 | LMNA (0.58) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9196493 | 0.92 | LMNA (0.60) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL7986036 | 0.91 | LMNA (0.57) | LMNACYP2C19HIF1AEGFRSRC | |
| Ioversol SCHEMBL7794872 | 0.91 | LMNA (0.65) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9317161 | 0.90 | LMNA (0.61) | LMNACYP2C19HIF1AEGFRSRC | |
| Ioversol SCHEMBL9489335 | 0.89 | LMNA (0.50) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9236621 | 0.88 | LMNA (0.59) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470247-B1 | REVERSED PHASE CHROMATOGRAPHIC PROCESS | MALLINCKRODT INC (US) | 1997-04-16 | — | — | EP | claimed |
| EP-0406992-B1 | New non-ionic carboxamide contrast agent | SCHERING AG (DE) | 1995-03-15 | — | — | EP | claimed |
| EP-0406992-A2 | New non-ionic carboxamide contrast agent | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-01-09 | — | — | EP | claimed |
| CN-118324652-A | Method for deiodination of X-CT iodine series contrast agent and intermediate benzene ring thereof | 浙江海洲制药股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-118026876-A | Preparation method of ioversol | 浙江海洲制药股份有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-117800986-A | Preparation method of ioversol impurity | 重庆圣华曦药业股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-117756660-A | Method for removing ioversol impurity | 重庆圣华曦药业股份有限公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-113717074-B | Method for preparing ioversol | 上海再启生物技术有限公司 | 2023-11-03 | — | — | CN | disclosed |
| CN-116768747-A | Intermediate of ioversol and method for preparing ioversol | 江苏宇田医药有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-116283644-A | Preparation method of ioversol | 安庆朗坤药业有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-115806500-A | Synthesis of ioversol polysubstituent | 大道隆达（北京）医药科技发展有限公司 | 2023-03-17 | — | — | CN | disclosed |
| CN-113717074-A | Method for preparing ioversol | 上海再启生物技术有限公司 | 2021-11-30 | — | — | CN | disclosed |
| CN-113050374-A | Photoresist composition and method for manufacturing semiconductor device | 台湾积体电路制造股份有限公司 | 2021-06-29 | — | — | CN | disclosed |
| EP-0762900-B1 | IMPROVED SYNTHESIS OF IOVERSOL USING PHOSPHORIC ACID MODIFIED CO-ADDITION | MALLINCKRODT INC (US) | 2001-11-21 | — | — | EP | disclosed |
| EP-0886634-A4 | PROCESS FOR PRODUCING IOVERSOL | MALLINCKRODT MEDICAL INC (US) | 2000-08-02 | — | — | EP | disclosed |
| EP-0886634-A1 | PROCESS FOR PRODUCING IOVERSOL | MALLINCKRODT MEDICAL, INC. (US) | 1998-12-30 | — | — | EP | disclosed |
| US-5698739-A | RADIOLOGY | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-16 | — | — | US | disclosed |
| WO-1997027172-A1 | PROCESS FOR PRODUCING IOVERSOL | MALLINCKRODT MEDICAL, INC. (US) | 1997-07-31 | — | — | WO | disclosed |
| EP-0406992-B1 | New non-ionic carboxamide contrast agent | SCHERING AG (DE) | 1995-03-15 | — | — | EP | disclosed |
| US-5371278-A | Increasing reaction solution concentration and temperature | MALLINCKRODT MEDICAL PMC (US) | 1994-12-06 | — | — | US | disclosed |