SCHEMBL7201155

SCHEMBL7201155

CC(C)(C)[Si](C)(C)OC1=Cc2c(c3ccccc3c3ccccc23)C1=O

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PREP P48147 2/20 0.34
CA12 O43570 2/20 0.33
CA1 P00915 2/20 0.33
CA9 Q16790 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4438037 0.68 ALDH1A1 (0.44) PREPCA12CA1CA9
SCHEMBL7200342 0.67 BCHE (0.31)
SCHEMBL7198318 0.63
Hydrochloric Acid SCHEMBL7196878 0.63
SCHEMBL30556213 0.62 CA1 (0.38) PREPCA12CA1CA9
SCHEMBL9042423 0.61 MAPT (0.42)
SCHEMBL8582723 0.61 ERBB2 (0.50) PREPCA12CA1CA9
SCHEMBL13487423 0.61 PREP (0.34) PREPCA12CA1CA9
SCHEMBL2368966 0.61 PREP (0.45) PREPCA12CA1CA9
SCHEMBL17977218 0.61 LDHA (0.47) CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0880534-B1 HETEROATOM SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYST SYSTEMS AND METHODS FOR PREPARING THEM BOREALIS TECH OY (FI) 2003-12-17 EP disclosed
US-6277778-B1 COORDINATION CATALYSTS BOREALIS A/S (DK) 2001-08-21 US disclosed
EP-0880534-A1 HETEROATOM SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYST SYSTEMS AND METHODS FOR PREPARING THEM BOREALIS A/S (DK) 1998-12-02 EP disclosed
WO-1997028170-A1 HETEROATOM SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYST SYSTEMS AND METHODS FOR PREPARING THEM BOREALIS A/S (DK) 1997-08-07 WO disclosed