Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795331 | 0.91 | SMO (0.43) | OPRL1 | |
| SCHEMBL6503236 | 0.87 | MAPT (0.39) | OPRL1HTR2A | |
| SCHEMBL7133280 | 0.82 | SORT1 (0.43) | OPRL1 | |
| SCHEMBL7084422 | 0.81 | ITGB1 (0.44) | OPRL1LRRK2 | |
| SCHEMBL7080705 | 0.79 | SMO (0.49) | LRRK2 | |
| SCHEMBL6666513 | 0.77 | MTTP (0.40) | TRPV4HTR2A | |
| SCHEMBL7079416 | 0.76 | MAPT (0.44) | OPRL1SCN8ASCN10A | |
| SCHEMBL6795217 | 0.76 | SMO (0.47) | OPRL1 | |
| SCHEMBL7080695 | 0.75 | PPARG (0.49) | LRRK2SCN8ASCN10A | |
| SCHEMBL7079740 | 0.75 | SORT1 (0.43) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |