SCHEMBL7201330

SCHEMBL7201330

CC(Cc1ccccc1)c1[c]cccc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 0.45
SIGMAR1 Q99720 5/20 0.45
MAOA P21397 4/20 0.45
SLC6A2 P23975 3/20 0.45
SLC6A4 P31645 2/20 0.45
SLC6A3 Q01959 2/20 0.45
CYP2A6 P11509 1/20 0.45
ADORA2A P29274 1/20 0.45
ADORA1 P30542 1/20 0.45
SLC18A2 Q05940 1/20 0.42
CYP2D6 P10635 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
TRPA1 O75762 2/20 0.41
MAOB P27338 3/20 0.40
NISCH Q9Y2I1 3/20 0.40
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
HTR2A P28223 1/20 0.39
ADRA1A P35348 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL664142 0.81
SCHEMBL1145144 0.78 ALPI (0.42) TAAR1SIGMAR1MAOASLC6A2SLC6A4
SCHEMBL14675555 0.78 KMT2A (0.33) KMT2A
SCHEMBL25333 0.78 TSHR (0.42) TAAR1TRPA1
SCHEMBL1569600 0.76 TRPA1 (0.38) TAAR1TRPA1
SCHEMBL2698493 0.76 TAAR1 (0.30) TAAR1
SCHEMBL23982 0.76 TAAR1 (0.30) TAAR1
SCHEMBL2448820 0.76 LARS1 (0.33) TAAR1TRPA1
SCHEMBL534244 0.74 SMN1; SMN2 (0.36)
SCHEMBL4433093 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6607653-B1 Tin-copper alloy plating bath, tin-copper-bismuth alloy plating bath or tin-copper-silver alloy plating bath containing a soluble metal compound and a specific sulfur-containing compound. The plating bath of the alloy with DAIWA FINE CHEMICALS CO., LTD. (JP) 2003-08-19 US disclosed
US-5847006-A Therapeutic guanidines CAMBRIDGE NEUROSCIENCE, INC. (US) 1998-12-08 US disclosed