Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25333 | 0.81 | TSHR (0.42) | TAAR1 | |
| SCHEMBL2448820 | 0.79 | LARS1 (0.33) | TAAR1 | |
| SCHEMBL2698493 | 0.79 | TAAR1 (0.30) | TAAR1 | |
| SCHEMBL1569600 | 0.79 | TRPA1 (0.38) | TAAR1 | |
| SCHEMBL534244 | 0.78 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL8439918 | 0.76 | — | — | |
| SCHEMBL7201330 | 0.76 | TAAR1 (0.45) | TAAR1 | |
| SCHEMBL664142 | 0.76 | — | — | |
| SCHEMBL4586019 | 0.76 | — | — | |
| SCHEMBL22363023 | 0.75 | LMNA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588480-A2 | 3,4-DIHYDROPYRROLO[1,2-A]PYRAZINE-2,8(1H)-DICARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF& xA; | SANOFI (FR) | 2013-05-08 | — | — | EP | disclosed |
| WO-2011161537-A2 | 3,4-DIHYDROPYRROLO[1,2-A]PYRAZINE-2,8(1H)-DICARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2011-12-29 | — | — | WO | disclosed |