Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | CASP1 | P29466 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.55 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 12/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7195879 | 1.00 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL20302856 | 0.92 | RAB9A (0.64) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL1699197 | 0.90 | SMN1; SMN2 (0.70) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL9124310 | 0.89 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL7197815 | 0.89 | NPC1 (0.58) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL12411578 | 0.87 | RAB9A (0.69) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL10360622 | 0.85 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL10361283 | 0.85 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL8391733 | 0.85 | NPC1 (0.54) | NPC1RAB9ASMN1; SMN2HPGDMAPT | |
| SCHEMBL8391789 | 0.85 | SMN1; SMN2 (0.61) | NPC1RAB9ASMN1; SMN2HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596669-B1 | Comprising a support and two reversible heat-sensitive recording layers having different colors formed on the same side of the support, comprising colorless electron-donative dye precursor and an electron-accepting compound | MITSUBISHI PAPER MILLS LIMITED (JP) | 2003-07-22 | — | — | US | disclosed |