SCHEMBL7201389

SCHEMBL7201389

Cc1ccc(-c2nc(S)c[nH]2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 1/20 0.46
DCUN1D1 Q96GG9 1/20 0.42
NR1H2 P55055 1/20 0.40
NR1H3 Q13133 1/20 0.40
TNKS O95271 3/20 0.37
PARP1 P09874 3/20 0.37
TNKS2 Q9H2K2 3/20 0.37
TYMP P19971 1/20 0.36
MAPT P10636 4/20 0.36
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
RAB9A P51151 2/20 0.36
NPC1 O15118 1/20 0.36
TSHR P16473 1/20 0.36
NFKB1 P19838 1/20 0.36
CASP3 P42574 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
SENP7 Q9BQF6 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11546589 0.80 KDM4E (0.44) DCUN1D1NR1H2NR1H3TNKSTNKS2
SCHEMBL6647087 0.79 NISCH (0.48) NISCHDCUN1D1NR1H2NR1H3TNKS
SCHEMBL27456927 0.79 MTOR (0.42) NISCHDCUN1D1NR1H2NR1H3TNKS
SCHEMBL28694876 0.78 NISCH (0.47) NISCHDCUN1D1NR1H2NR1H3TNKS
SCHEMBL1233362 0.78 LMNA (0.40) MAPTALDH1A1KDM4EHPGDLMNA
SCHEMBL28959148 0.78 MTOR (0.41) NISCHDCUN1D1NR1H2NR1H3TNKS
SCHEMBL28009196 0.76 NISCH (0.46) NISCHDCUN1D1NR1H2NR1H3TNKS
SCHEMBL27576726 0.76 DCUN1D1 (0.46) NISCHDCUN1D1NR1H2NR1H3TNKS
SCHEMBL20390576 0.76 NISCH (0.46) NISCHDCUN1D1NR1H2NR1H3TNKS
SCHEMBL10269431 0.74 NISCH (0.44) NISCHDCUN1D1NR1H2NR1H3TNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0953597-B1 Improving heat aging of grafted polyolefins using zinc mercapto compounds BASELL POLIOLEFINE SPA (IT) 2003-09-17 EP disclosed
WO-2001036556-A2 FUEL BARRIER LAMINATE GOSHEN RUBBER CO., INC. (US) 2001-05-25 WO disclosed
EP-0953597-A2 Improving heat aging of grafted polyolefins using zinc mercapto compounds Montell North America Inc. (US) 1999-11-03 EP disclosed
US-5662200-A Clutch disc of a motor vehicle, which clutch disc has an elastic connection between the carrier plate and hub FICHTEL & SACHS AG (DE) 1997-09-02 US disclosed
EP-0483737-B1 Cured blends of polychloroprene and ethylene copolymers DU PONT (US) 1995-02-15 EP disclosed
EP-0585202-A1 N,N'-alkenylene amine/mercaptotolyl-imidazole blends as high temperature antioxidants for elastomers CIBA-GEIGY AG (CH) 1994-03-02 EP disclosed
EP-0585202-A1 N,N'-alkenylene amine/mercaptotolyl-imidazole blends as high temperature antioxidants for elastomers CIBA-GEIGY AG (CH) 1994-03-02 EP disclosed
US-5240976-A For automobile, wire and cable uses CIBA-GEIGY CORPORATION (US) 1993-08-31 US disclosed
US-5240976-A For automobile, wire and cable uses CIBA-GEIGY CORPORATION (US) 1993-08-31 US disclosed
US-5208294-A Wear and heat resistance POLYSAR RUBBER CORPORATION (CA) 1993-05-04 US disclosed
US-5140072-A Flex crack growth resistance E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-08-18 US disclosed
EP-0483737-A1 Cured blends of polychloroprene and ethylene copolymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-05-06 EP disclosed
US-4419475-A Heat resistant ethylene-propylene rubber with improved tensile properties and insulated conductor product thereof GENERAL ELECTRIC COMPANY (US) 1983-12-06 US disclosed
US-4303574-A Heat resistant ethylene-propylene rubber with improved tensile properties and insulated conductor product thereof GENERAL ELECTRIC COMPANY (US) 1981-12-01 US disclosed