SCHEMBL28009196

SCHEMBL28009196

Cc1ccc(-c2nc(Cl)c[nH]2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 1/20 0.46
DCUN1D1 Q96GG9 1/20 0.42
NR1H2 P55055 1/20 0.40
NR1H3 Q13133 1/20 0.40
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
TNKS O95271 3/20 0.37
PARP1 P09874 3/20 0.37
TNKS2 Q9H2K2 3/20 0.37
TYMP P19971 1/20 0.36
NR1H4 Q96RI1 1/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22165987 0.80 DGAT1 (0.40) NR1H2NR1H3MAPTALDH1A1TNKS
SCHEMBL10554127 0.80 ALOX12 (0.44) MEN1KMT2AMAPTHPGDALDH1A1
SCHEMBL9271844 0.79 MTOR (0.42) NISCHDCUN1D1NR1H2NR1H3MEN1
SCHEMBL6647087 0.79 NISCH (0.48) NISCHDCUN1D1NR1H2NR1H3MEN1
SCHEMBL28694876 0.78 NISCH (0.47) NISCHDCUN1D1NR1H2NR1H3MEN1
SCHEMBL19052768 0.76 NPC1 (0.51) MEN1KMT2AKDM4EALDH1A1TDP1
SCHEMBL20390576 0.76 NISCH (0.46) NISCHDCUN1D1NR1H2NR1H3MEN1
SCHEMBL7201389 0.76 NISCH (0.46) NISCHDCUN1D1NR1H2NR1H3MEN1
SCHEMBL27576726 0.76 DCUN1D1 (0.46) NISCHDCUN1D1NR1H2NR1H3MEN1
SCHEMBL27346201 0.75 KDM4E (0.53) MAPTHPGDKDM4EALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104650090-B A kind of fluorene kind derivative of the bases of -3- containing carbazole group and its application 固安鼎材科技有限公司 2018-05-18 CN disclosed
CN-104650116-B A kind of organic compound and its application in organic electroluminescence device 北京鼎材科技有限公司 2017-12-05 CN disclosed
CN-104650089-B A kind of fluorene kind derivative of base group containing carbazole 9 and its application 固安鼎材科技有限公司 2017-10-03 CN disclosed
CN-104650088-B A kind of derivative of carbazolyl-containing and its application in organic electroluminescence device 固安鼎材科技有限公司 2017-08-01 CN disclosed
CN-104650117-B A kind of organic compound and its application in organic electroluminescence device 北京鼎材科技有限公司 2017-08-01 CN disclosed
CN-104672240-A Carbazole type derivative and application thereof in organic electroluminescent device BEIJING ETERNAL MATERIAL TECHNOLOGY CO LTD 2015-06-03 CN disclosed
CN-104650089-A Fluorene derivative containing carbazole-9-yl group and application thereof BEIJING ETERNAL MATERIAL TECHNOLOGY CO LTD 2015-05-27 CN disclosed
CN-104650117-A Organic compound and application thereof in organic electroluminescence devices BEIJING ETERNAL MATERIAL TECHNOLOGY CO LTD 2015-05-27 CN disclosed
CN-104650116-A Organic compound and application thereof in organic electroluminescence devices BEIJING ETERNAL MATERIAL TECHNOLOGY CO LTD 2015-05-27 CN disclosed
CN-104650088-A Carbazolyl-containing derivative and application thereof in organic electroluminescence devices BEIJING ETERNAL MATERIAL TECHNOLOGY CO LTD 2015-05-27 CN disclosed
CN-104650090-A Fluorene derivative containing carbazole-3-yl group and application thereof BEIJING ETERNAL MATERIAL TECHNOLOGY CO LTD 2015-05-27 CN disclosed