Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 7/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 6/20 | 0.40 |
| ▸ | HTR2C | P28335 | 6/20 | 0.40 |
| ▸ | HTR7 | P34969 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877687 | 0.89 | TAS2R14 (0.60) | TAS2R14CNR1CNR2TP53HTR2A | |
| SCHEMBL7206004 | 0.89 | TAS2R14 (0.60) | TAS2R14CNR1CNR2TP53HTR2A | |
| SCHEMBL7200685 | 0.88 | TAS2R14 (0.61) | TAS2R14CNR1CNR2TP53HTR2A | |
| SCHEMBL7202825 | 0.86 | TAS2R14 (0.60) | TAS2R14CNR1CNR2TP53HTR2A | |
| SCHEMBL7201207 | 0.86 | TAS2R14 (0.60) | TAS2R14CNR1CNR2TP53HTR2A | |
| SCHEMBL7201049 | 0.86 | TAS2R14 (0.60) | TAS2R14CNR1CNR2TP53HTR2A | |
| SCHEMBL7201426 | 0.86 | TAS2R14 (0.60) | TAS2R14CNR1CNR2TP53HTR2A | |
| SCHEMBL7206786 | 0.86 | TAS2R14 (0.60) | TAS2R14CNR1CNR2TP53HTR2A | |
| SCHEMBL7207466 | 0.86 | TAS2R14 (0.60) | TAS2R14CNR1CNR2TP53HTR2A | |
| SCHEMBL7091999 | 0.84 | ALDH1A1 (0.49) | CNR2CA12CA9CA1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605645-B2 | Such as 1,15-di(cyclopropylmethylamino)-8-benzyl-4,8,12-triazapentadecane; carcinostatic action | RIKEN (JP) | 2003-08-12 | — | — | US | disclosed |
| US-20020067472-A1 | Linear polyamine compounds and polyamine anticancer agents | IWATA MASAAKI (JP) | 2002-06-06 | — | — | US | disclosed |
| US-6319956-B1 | N1, N4-BIS(CYCLOPROPYLMETHYLAMINO)TRIALKYLENETETRAMINES THAT MAY BE TOLUENESULFONATED. | RIKEN (JP) | 2001-11-20 | — | — | US | disclosed |