Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5058493 | 0.76 | LMNA (0.52) | CA2CA4ALDH1A1LMNATDP1 | |
| SCHEMBL8949923 | 0.74 | TDP1 (0.34) | CA2CA4ALDH1A1LMNATDP1 | |
| SCHEMBL2545055 | 0.74 | FOLH1 (0.52) | CA2CA4LMNATDP1FOLH1 | |
| SCHEMBL8628287 | 0.72 | FOLH1 (0.50) | CA2CA4LMNATDP1FOLH1 | |
| SCHEMBL11204832 | 0.72 | FOLH1 (0.50) | CA2CA4LMNATDP1FOLH1 | |
| SCHEMBL11259298 | 0.71 | ALDH1A1 (0.50) | ALDH1A1LMNATDP1MAPTPTGS2 | |
| SCHEMBL622444 | 0.71 | ALDH1A1 (0.50) | ALDH1A1LMNATDP1MAPTPTGS2 | |
| SCHEMBL14803345 | 0.70 | ALDH1A1 (0.48) | ALDH1A1LMNATDP1MAPTPTGS2 | |
| SCHEMBL13589987 | 0.70 | SMN1; SMN2 (0.54) | ALDH1A1LMNATDP1MAPTPTGS2 | |
| SCHEMBL4101490 | 0.70 | FOLH1 (0.39) | CA2CA4LMNATDP1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6607710-B1 | Provide a bisphosphonic acid derivative and said bisphosphonic acid derivative being labeled with a radioactive nuclide, which has properties of rapid accumulation to the bone and rapid urinary excretion. | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2003-08-19 | — | — | US | disclosed |
| EP-1092723-A2 | Bisphosphonic acid derivative and compound thereof labelled with radioactive nuclide | NIHON MEDI-PHYSICS Co., Ltd. (JP) | 2001-04-18 | — | — | EP | disclosed |