Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189140 | 0.88 | TACR1 (0.41) | HTR2ATACR1CTNNB1CYP1A2CYP2C19 | |
| SCHEMBL7194271 | 0.85 | TLR8 (0.40) | HTR2ATACR1CTNNB1CYP1A2CYP2C19 | |
| SCHEMBL7191436 | 0.84 | TLR8 (0.41) | HTR2ATACR1KMT2A | |
| SCHEMBL7190392 | 0.83 | TLR8 (0.41) | HTR2ATACR1KMT2A | |
| SCHEMBL7183650 | 0.83 | TLR8 (0.41) | HTR2ATACR1KMT2A | |
| SCHEMBL2992860 | 0.77 | MEN1 (0.49) | CTNNB1CYP1A2CYP2C19CYP2D6MEN1 | |
| SCHEMBL11654244 | 0.75 | HTR2A (0.45) | HTR2ATACR1 | |
| SCHEMBL2906023 | 0.75 | KMT2A (0.51) | CTNNB1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL1537099 | 0.74 | CYP1A2 (0.44) | CYP1A2CYP2C19CYP2D6MEN1ALDH1A1 | |
| SCHEMBL27896460 | 0.73 | DPP4 (0.53) | HTR2ACYP1A2CYP2C19CYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586376-B1 | Sterically hindered polyol ester and polyphenyl thioether, oxidation resistance; jet turbine engines | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2003-07-01 | — | — | US | disclosed |
| US-6191080-B1 | MIXTURE OF POLYOL ESTERS, MIXTURE OF POLYPHENYLENE ETHER AND POLYOL ESTER AND POLYPHENYLENE THIOETHERS | TONEN CORPORATION (JP) | 2001-02-20 | — | — | US | disclosed |
| EP-0778334-A1 | HEAT-RESISTANT LUBRICATING OIL COMPOSITION | Tonen Corporation (JP) | 1997-06-11 | — | — | EP | disclosed |