Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7191436 | 0.96 | TLR8 (0.41) | TLR8TACR1CNR2HTR2ACNR1 | |
| SCHEMBL7190392 | 0.94 | TLR8 (0.41) | TLR8TACR1CNR2HTR2ACNR1 | |
| SCHEMBL7183650 | 0.94 | TLR8 (0.41) | TLR8TACR1CNR2HTR2ACNR1 | |
| SCHEMBL7189140 | 0.91 | TACR1 (0.41) | TLR8TACR1CNR2HTR2ACTNNB1 | |
| SCHEMBL7202017 | 0.85 | HTR2A (0.49) | TACR1HTR2ACTNNB1KCNA5KCNH2 | |
| SCHEMBL1990279 | 0.77 | ALOX5 (0.45) | TLR8CNR2CNR1CYP1A2CYP2C19 | |
| Phosphine SCHEMBL28863280 | 0.75 | CNR2 (0.46) | TLR8CNR2CNR1CYP1A2CYP2D6 | |
| SCHEMBL6058810 | 0.75 | CNR1 (0.49) | TLR8CNR2KCNH2CNR1CYP1A2 | |
| SCHEMBL24148832 | 0.75 | SIGMAR1 (0.40) | CNR2HTR2A | |
| SCHEMBL28053357 | 0.74 | CNR1 (0.50) | TLR8CNR2KCNH2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586376-B1 | Sterically hindered polyol ester and polyphenyl thioether, oxidation resistance; jet turbine engines | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2003-07-01 | — | — | US | disclosed |
| US-6191080-B1 | MIXTURE OF POLYOL ESTERS, MIXTURE OF POLYPHENYLENE ETHER AND POLYOL ESTER AND POLYPHENYLENE THIOETHERS | TONEN CORPORATION (JP) | 2001-02-20 | — | — | US | disclosed |
| EP-0778334-A1 | HEAT-RESISTANT LUBRICATING OIL COMPOSITION | Tonen Corporation (JP) | 1997-06-11 | — | — | EP | disclosed |