Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7190392 | 1.00 | TLR8 (0.41) | TLR8KDM4EKMT2AL3MBTL1CSNK1E | |
| SCHEMBL7191436 | 0.99 | TLR8 (0.41) | TLR8KDM4EKMT2AL3MBTL1CSNK1E | |
| SCHEMBL7194271 | 0.94 | TLR8 (0.40) | TLR8CNR1TACR1CNR2HTR2A | |
| SCHEMBL7189140 | 0.89 | TACR1 (0.41) | TLR8KMT2ATACR1CNR2HTR2A | |
| SCHEMBL7202017 | 0.83 | HTR2A (0.49) | KMT2ATACR1HTR2A | |
| Decane SCHEMBL9931523 | 0.79 | CNR1 (0.51) | TLR8KDM4EKMT2ACNR1CNR2 | |
| Tetradecane SCHEMBL9931525 | 0.79 | CNR1 (0.51) | TLR8KDM4EKMT2ACNR1CNR2 | |
| SCHEMBL28878838 | 0.78 | CSNK1E (0.42) | CSNK1E | |
| SCHEMBL28053357 | 0.78 | CNR1 (0.50) | TLR8CNR1CNR2 | |
| SCHEMBL1990198 | 0.78 | ALOX5 (0.43) | TLR8KDM4EKMT2AL3MBTL1CSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586376-B1 | Sterically hindered polyol ester and polyphenyl thioether, oxidation resistance; jet turbine engines | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2003-07-01 | — | — | US | disclosed |
| US-6191080-B1 | MIXTURE OF POLYOL ESTERS, MIXTURE OF POLYPHENYLENE ETHER AND POLYOL ESTER AND POLYPHENYLENE THIOETHERS | TONEN CORPORATION (JP) | 2001-02-20 | — | — | US | disclosed |
| EP-0790294-A2 | Lubricating compositions | The Lubrizol Corporation (US) | 1997-08-20 | — | — | EP | disclosed |
| EP-0778334-A1 | HEAT-RESISTANT LUBRICATING OIL COMPOSITION | Tonen Corporation (JP) | 1997-06-11 | — | — | EP | disclosed |