Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200053 | 0.90 | HDAC4 (0.54) | HDAC4KMT2AMEN1PGRTP53 | |
| SCHEMBL10676102 | 0.89 | MEN1 (0.63) | HDAC4KMT2AMEN1PGRALDH1A1 | |
| SCHEMBL7203423 | 0.88 | HDAC4 (0.52) | HDAC4KMT2AMEN1PGRALDH1A1 | |
| SCHEMBL10676414 | 0.85 | HDAC4 (0.63) | HDAC4KMT2AMEN1PGRTP53 | |
| SCHEMBL5163633 | 0.84 | HDAC4 (0.62) | HDAC4KMT2AMEN1PGRTP53 | |
| SCHEMBL7236279 | 0.84 | HDAC4 (0.62) | HDAC4KMT2AMEN1PGRTP53 | |
| SCHEMBL7612553 | 0.82 | HDAC4 (0.58) | HDAC4KMT2AMEN1PGRTP53 | |
| SCHEMBL7619676 | 0.82 | HDAC4 (0.60) | HDAC4KMT2AMEN1PGRTP53 | |
| SCHEMBL7245512 | 0.81 | HDAC4 (0.69) | HDAC4KMT2AMEN1PGRTP53 | |
| SCHEMBL8145505 | 0.81 | HDAC4 (0.59) | HDAC4KMT2AMEN1PGRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605616-B1 | Autoimmune diseases; inflammation | ACTIVE BIOTECH AB (SE) | 2003-08-12 | — | — | US | disclosed |