Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10676102 | 0.93 | MEN1 (0.63) | HDAC4MEN1KMT2APGRSRC | |
| SCHEMBL7203423 | 0.92 | HDAC4 (0.52) | HDAC4MEN1KMT2APGRSRC | |
| SCHEMBL7202036 | 0.90 | HDAC4 (0.58) | HDAC4MEN1KMT2APGRSRC | |
| SCHEMBL5165352 | 0.82 | HDAC4 (0.58) | HDAC4MEN1KMT2APGRSRC | |
| SCHEMBL7202009 | 0.82 | HDAC4 (0.58) | HDAC4MEN1KMT2APGRSRC | |
| SCHEMBL19398184 | 0.81 | HDAC4 (0.79) | HDAC4MEN1KMT2APGRSRC | |
| SCHEMBL10674240 | 0.80 | HDAC4 (0.41) | HDAC4MEN1KMT2APGRRXFP1 | |
| SCHEMBL7204453 | 0.79 | ALDH1A1 (0.60) | MEN1KMT2ANPC1ALDH1A1KDM4E | |
| SCHEMBL5167153 | 0.78 | MEN1 (0.70) | HDAC4MEN1KMT2APGRSRC | |
| SCHEMBL5166744 | 0.77 | HDAC4 (0.57) | HDAC4MEN1KMT2APGRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605616-B1 | Autoimmune diseases; inflammation | ACTIVE BIOTECH AB (SE) | 2003-08-12 | — | — | US | disclosed |