Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 9/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7200053 | 0.92 | HDAC4 (0.54) | HDAC4MEN1KMT2APGRSRC | |
| SCHEMBL10676102 | 0.91 | MEN1 (0.63) | HDAC4MEN1KMT2APGRSRC | |
| SCHEMBL7202036 | 0.88 | HDAC4 (0.58) | HDAC4MEN1KMT2APGRGPBAR1 | |
| SCHEMBL5165280 | 0.85 | HDAC4 (0.58) | HDAC4MEN1KMT2APGRGPBAR1 | |
| SCHEMBL5166744 | 0.84 | HDAC4 (0.57) | HDAC4MEN1KMT2APGRGPBAR1 | |
| SCHEMBL7618291 | 0.82 | HDAC4 (0.52) | HDAC4MEN1KMT2APGRGPBAR1 | |
| SCHEMBL7002185 | 0.81 | HDAC4 (0.76) | HDAC4MEN1KMT2APGRGPBAR1 | |
| SCHEMBL7623491 | 0.81 | HDAC4 (0.54) | HDAC4MEN1KMT2APGRGPBAR1 | |
| SCHEMBL6999935 | 0.80 | HDAC4 (0.63) | HDAC4MEN1KMT2APGRGPBAR1 | |
| SCHEMBL7558495 | 0.80 | HDAC4 (0.53) | HDAC4MEN1KMT2APGRGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605616-B1 | Autoimmune diseases; inflammation | ACTIVE BIOTECH AB (SE) | 2003-08-12 | — | — | US | disclosed |