Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.80 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | FAAH | O00519 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31632624 | 1.00 | TSHR (0.80) | TSHRSMN1; SMN2MAPTFAAHHPGD | |
| SCHEMBL3262559 | 0.92 | TSHR (0.79) | TSHRSMN1; SMN2MAPTFAAHHPGD | |
| SCHEMBL26092952 | 0.92 | TSHR (0.95) | TSHRSMN1; SMN2MAPTFAAHHPGD | |
| SCHEMBL26094938 | 0.92 | TSHR (0.95) | TSHRSMN1; SMN2MAPTFAAHHPGD | |
| SCHEMBL25702503 | 0.92 | TSHR (0.95) | TSHRSMN1; SMN2MAPTFAAHHPGD | |
| SCHEMBL6687715 | 0.89 | TSHR (1.00) | TSHRSMN1; SMN2MAPTFAAHHPGD | |
| SCHEMBL11327844 | 0.84 | TSHR (0.80) | TSHRSMN1; SMN2MAPTFAAHHPGD | |
| SCHEMBL6886771 | 0.84 | TSHR (0.80) | TSHRSMN1; SMN2MAPTFAAHHPGD | |
| SCHEMBL22508718 | 0.84 | TSHR (0.80) | TSHRSMN1; SMN2MAPTFAAHHPGD | |
| SCHEMBL7037455 | 0.84 | TSHR (0.80) | TSHRSMN1; SMN2MAPTFAAHHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030144551-A1 | Methods of making intermediates from polyhydroxyalkanoates | CJ CHEILJEDANG CORPORATION (KR) | 2003-07-31 | — | — | US | claimed |
| WO-2003051813-A1 | METHODS OF MAKING INTERMEDIATES FROM POLYHYDROXYALKANOATES | METABOLIX, INC. (US) | 2003-06-26 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144551-A1 | Methods of making intermediates from polyhydroxyalkanoates | HMBS, COASY, PGLS | TSHR 4408/4885SMN1; SMN2 4878/4885MAPT 4739/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.