Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 14/20 | 0.79 |
| ▸ | THRA | P10827 | 12/20 | 0.79 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | GABRP | O00591 | 1/20 | 0.57 |
| ▸ | GABRD | O14764 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | F2 | P00734 | 1/20 | 0.57 |
| ▸ | PCNA | P12004 | 1/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.57 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.57 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.57 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.57 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.57 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.57 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202122 | 1.00 | THRB (0.79) | THRBTHRALMNACYP2D6TSHR | |
| SCHEMBL7277669 | 0.90 | THRB (0.84) | THRBTHRALMNACYP2D6TSHR | |
| SCHEMBL7277661 | 0.90 | THRB (0.84) | THRBTHRALMNACYP2D6TSHR | |
| SCHEMBL3219497 | 0.88 | THRB (1.00) | THRBTHRALMNACYP2D6TSHR | |
| SCHEMBL3219487 | 0.88 | THRB (1.00) | THRBTHRALMNACYP2D6TSHR | |
| SCHEMBL5549652 | 0.88 | THRB (1.00) | THRBTHRALMNACYP2D6TSHR | |
| SCHEMBL5549347 | 0.86 | THRB (0.79) | THRBTHRA | |
| SCHEMBL9170207 | 0.86 | THRB (1.00) | THRBTHRALMNACYP2D6TSHR | |
| SCHEMBL5549351 | 0.86 | THRB (0.79) | THRBTHRA | |
| SCHEMBL9619560 | 0.86 | THRB (1.00) | THRBTHRALMNACYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0831769-B1 | NOVEL USES FOR THYROID HORMONES OR THYROID HORMONE-LIKE COMPOUNDS | KAROBIO AB (SE) | 2003-10-15 | — | — | EP | claimed |