Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749085 | 0.90 | NTRK1 (0.48) | GNRHRLMNAHTTNTRK1IGF1R | |
| SCHEMBL4248933 | 0.87 | ALDH1A1 (0.46) | GNRHRLMNAHTTALDH1A1MEN1 | |
| SCHEMBL7747096 | 0.81 | ALDH1A1 (0.46) | GNRHRLMNANTRK1IGF1RFGFR1 | |
| SCHEMBL29382466 | 0.79 | APP (0.34) | GNRHRLMNAAPPMEN1KMT2A | |
| SCHEMBL29696460 | 0.75 | SLC11A2 (0.37) | GNRHRHTTALDH1A1MEN1KMT2A | |
| SCHEMBL29696469 | 0.74 | SLC11A2 (0.37) | GNRHRLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL29696456 | 0.73 | SLC11A2 (0.38) | GNRHRHTTALDH1A1MEN1KMT2A | |
| SCHEMBL29696435 | 0.72 | SLC11A2 (0.37) | GNRHRHTTALDH1A1MEN1KMT2A | |
| SCHEMBL29696443 | 0.72 | SLC11A2 (0.37) | GNRHRHTTALDH1A1MEN1KMT2A | |
| SCHEMBL29696450 | 0.72 | SLC11A2 (0.35) | GNRHRLMNAHTTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808317-B1 | THIENOPYRIMIDINE DERIVATIVES, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-09-10 | — | — | EP | disclosed |