Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC11A2 | P49281 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | TNKS | O95271 | 4/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | GNRHR | P30968 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | GUSB | P08236 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29696435 | 0.90 | SLC11A2 (0.37) | SLC11A2FLT3TNKSTNKS2PARP1 | |
| SCHEMBL29696469 | 0.86 | SLC11A2 (0.37) | SLC11A2FLT3PARP1GNRHRALDH1A1 | |
| SCHEMBL29696450 | 0.85 | SLC11A2 (0.35) | SLC11A2FLT3GNRHRALDH1A1HTT | |
| SCHEMBL29696424 | 0.78 | GNRHR (0.57) | GNRHR | |
| SCHEMBL29696443 | 0.78 | SLC11A2 (0.37) | SLC11A2FLT3GNRHRALDH1A1HTT | |
| SCHEMBL4248933 | 0.77 | ALDH1A1 (0.46) | GNRHRALDH1A1POLBHTTMEN1 | |
| SCHEMBL29696460 | 0.77 | SLC11A2 (0.37) | SLC11A2FLT3GNRHRALDH1A1HTT | |
| SCHEMBL29382466 | 0.75 | APP (0.34) | SLC11A2FLT3TNKSTNKS2PARP1 | |
| SCHEMBL7202144 | 0.73 | GNRHR (0.46) | GNRHRALDH1A1POLBHTTMEN1 | |
| SCHEMBL29696377 | 0.70 | GNRHR (0.57) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4004001-B1 | SUBSTITUTED PYRIMIDINEDIONE COMPOUNDS AND USES THEREOF | SUNSHINE LAKE PHARMA CO LTD (CN) | 2025-09-03 | — | — | EP | disclosed |
| US-20220267347-A1 | SUBSTITUTED PYRIMIDINEDIONE COMPOUNDS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-08-25 | — | — | US | disclosed |
| EP-4004001-A1 | SUBSTITUTED PYRIMIDINEDIONE COMPOUNDS AND USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2022-06-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267347-A1 | SUBSTITUTED PYRIMIDINEDIONE COMPOUNDS AND USES THEREOF | GNRHR, CDK20, PGR | SLC11A2 4361/4885FLT3 769/4885TNKS 585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.