Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM5A | P29375 | 3/20 | 0.43 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | ICMT | O60725 | 1/20 | 0.40 |
| ▸ | ALB | P02768 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL7202255 | 1.00 | TP53 (0.46) | TP53NPSR1KDM5APHF8MCHR1 | |
| Sulfuric Acid SCHEMBL28829383 | 0.97 | DNM1 (0.46) | TP53NPSR1KDM5APHF8MCHR1 | |
| Sulfuric Acid SCHEMBL29702498 | 0.97 | DNM1 (0.46) | TP53NPSR1KDM5APHF8MCHR1 | |
| Sulfuric Acid SCHEMBL2421781 | 0.97 | DNM1 (0.46) | TP53NPSR1KDM5APHF8MCHR1 | |
| Sulfuric Acid SCHEMBL8991567 | 0.97 | DNM1 (0.46) | TP53NPSR1KDM5APHF8MCHR1 | |
| Sulfuric Acid SCHEMBL8991563 | 0.97 | DNM1 (0.46) | TP53NPSR1KDM5APHF8MCHR1 | |
| Sulfuric Acid SCHEMBL3069416 | 0.97 | DNM1 (0.46) | TP53NPSR1KDM5APHF8MCHR1 | |
| Sulfuric Acid SCHEMBL28069559 | 0.97 | DNM1 (0.46) | TP53NPSR1KDM5APHF8MCHR1 | |
| Sulfuric Acid SCHEMBL7196007 | 0.95 | KDM5A (0.49) | TP53NPSR1KDM5APHF8MCHR1 | |
| Sulfuric Acid SCHEMBL2524039 | 0.95 | KDM5A (0.44) | TP53NPSR1KDM5APHF8MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596911-B2 | Providing a mixture comprising water and a hydrocarbon; and contacting with onium compound and amine salt for inhibiting the formation of the hydrocarbon hydrates | BAKER HUGHES INCORPORATION | 2003-07-22 | — | — | US | claimed |
| EP-0736130-B1 | A METHOD FOR INHIBITING THE PLUGGING OF CONDUITS BY GAS HYDRATES | SHELL INT RESEARCH (NL) | 1998-07-15 | — | — | EP | disclosed |
| US-5648575-A | Method for inhibiting the plugging of conduits by gas hydrates | SHELL OIL COMPANY (US) | 1997-07-15 | — | — | US | disclosed |
| EP-0736130-A1 | A METHOD FOR INHIBITING THE PLUGGING OF CONDUITS BY GAS HYDRATES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1996-10-09 | — | — | EP | disclosed |
| US-5460728-A | Using quaternary ammonium compound as inhibitor of hydrate formation | SHELL OIL COMPANY (US) | 1995-10-24 | — | — | US | disclosed |
| WO-1995017579-A1 | A METHOD FOR INHIBITING THE PLUGGING OF CONDUITS BY GAS HYDRATES | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 1995-06-29 | — | — | WO | disclosed |