Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202005 | 0.89 | SMN1; SMN2 (0.50) | ALDH1A1SMN1; SMN2NPC1RAB9AERCC5 | |
| SCHEMBL7203229 | 0.84 | TP53 (0.47) | ALDH1A1TP53SMN1; SMN2ERCC5FEN1 | |
| SCHEMBL7203523 | 0.79 | RAB9A (0.49) | ALDH1A1TP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7205482 | 0.78 | MAPT (0.52) | SMN1; SMN2NPC1RAB9ALMNAMEN1 | |
| SCHEMBL7205899 | 0.78 | PARP1 (0.44) | ALDH1A1SMN1; SMN2NPC1RAB9AERCC5 | |
| SCHEMBL7845827 | 0.78 | CNR2 (0.40) | ALDH1A1SMN1; SMN2NPC1RAB9ACNR2 | |
| SCHEMBL7832775 | 0.73 | RAB9A (0.43) | ALDH1A1TP53SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7199134 | 0.72 | CTNNB1 (0.50) | ALDH1A1NPC1RAB9AERCC5FEN1 | |
| SCHEMBL29693871 | 0.72 | CTNNB1 (0.50) | ALDH1A1NPC1RAB9AERCC5FEN1 | |
| SCHEMBL28454253 | 0.72 | RAB9A (0.50) | ALDH1A1SMN1; SMN2NPC1RAB9AERCC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6605730-B2 | 3-(2-Thienyl)-5-phenyl-1H-pyrazole compounds of given formula | NIHON BAYER AGROCHEM K.K. (JP) | 2003-08-12 | — | — | US | disclosed |
| US-20030028034-A1 | Nematicidal pyrazoles | WADA KATSUAKI (JP) | 2003-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030028034-A1 | Nematicidal pyrazoles | CBR3, CBR1, CCR4 | ALDH1A1 1476/4885TP53 4681/4885SMN1; SMN2 3988/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.