Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Docosanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.92 |
| ▸ | THRB | P10828 | 2/20 | 0.61 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanol SCHEMBL620143 | 1.00 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Decanol SCHEMBL16673240 | 1.00 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Nonanol SCHEMBL1403551 | 1.00 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Cetostearyl Alcohol SCHEMBL9513490 | 1.00 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL2884866 | 1.00 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL25421234 | 1.00 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Cetostearyl Alcohol SCHEMBL20515901 | 1.00 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Docosanol SCHEMBL21218972 | 1.00 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Myristyl Alcohol SCHEMBL21352636 | 1.00 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A | |
| Octacosanol SCHEMBL4801577 | 1.00 | LMNA (1.00) | LMNAALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596776-B2 | Subjecting a natural product starting material containing primary aliphatic alcohols to liquid extraction with a liquid organic extractant in which alcohols are soluble; recovering alcohol mixture | HAUSER, INC. | 2003-07-22 | — | — | US | disclosed |