Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202449 | 1.00 | APOBEC3G (0.46) | APOBEC3GTAS1R3TAS1R1ALDH1A1HPGD | |
| SCHEMBL7204083 | 0.87 | TAS1R3 (0.51) | TAS1R3TAS1R1ALPLRAB9APDE4A | |
| SCHEMBL5053376 | 0.87 | TAS1R3 (0.51) | TAS1R3TAS1R1ALPLRAB9APDE4A | |
| SCHEMBL5735842 | 0.85 | TAS1R3 (0.48) | APOBEC3GTAS1R3TAS1R1ALDH1A1HPGD | |
| SCHEMBL5735847 | 0.85 | TAS1R3 (0.48) | APOBEC3GTAS1R3TAS1R1ALDH1A1HPGD | |
| SCHEMBL6167355 | 0.84 | PDE4B (0.53) | APOBEC3GTAS1R3TAS1R1ALDH1A1HPGD | |
| SCHEMBL6167359 | 0.84 | PDE4B (0.53) | APOBEC3GTAS1R3TAS1R1ALDH1A1HPGD | |
| SCHEMBL5734204 | 0.84 | PDE4B (0.53) | APOBEC3GTAS1R3TAS1R1ALDH1A1HPGD | |
| SCHEMBL5734199 | 0.84 | PDE4B (0.53) | APOBEC3GTAS1R3TAS1R1ALDH1A1HPGD | |
| SCHEMBL5735482 | 0.83 | PDE4B (0.52) | APOBEC3GTAS1R3TAS1R1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882021-B1 | NEW PHENANTHRIDINES | ALTANA PHARMA AG (DE) | 2003-03-05 | — | — | EP | disclosed |
| US-6191138-B1 | THERAPY FOR RESPIRATORY SYSTEM DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2001-02-20 | — | — | US | disclosed |