SCHEMBL7202492

SCHEMBL7202492

C=CCOc1ccc(-c2nc(-c3ccc(OCC=C)cc3O)nc(-c3ccc(OCC=C)cc3O)n2)c(O)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.54
LMNA P02545 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
GAA P10253 4/20 0.47
HPGD P15428 2/20 0.47
ALDH1A1 P00352 1/20 0.47
SLC5A1 P13866 1/20 0.45
SLC5A2 P31639 1/20 0.45
CA12 O43570 5/20 0.44
CA1 P00915 5/20 0.44
CA9 Q16790 5/20 0.44
NPC1 O15118 1/20 0.44
ALDH2 P05091 1/20 0.43
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
CA2 P00918 1/20 0.42
CA7 P43166 1/20 0.42
ADRA2A P08913 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30887114 0.90 MAPT (0.50) MAPTLMNASMN1; SMN2MEN1KMT2A
SCHEMBL7944222 0.90 MAPT (0.50) MAPTLMNASMN1; SMN2MEN1KMT2A
SCHEMBL30887140 0.88 MAPT (0.53) MAPTLMNASMN1; SMN2MEN1KMT2A
SCHEMBL30887160 0.88 MAPT (0.48) MAPTLMNASMN1; SMN2MEN1KMT2A
SCHEMBL31583003 0.88 HPGD (0.53) MAPTLMNASMN1; SMN2MEN1KMT2A
SCHEMBL5584199 0.88 MAPT (0.48) MAPTLMNASMN1; SMN2MEN1KMT2A
SCHEMBL5141058 0.88 MAPT (0.48) MAPTLMNASMN1; SMN2MEN1KMT2A
SCHEMBL31583281 0.88 MAPT (0.48) MAPTLMNASMN1; SMN2MEN1KMT2A
SCHEMBL31582978 0.84 MAPT (0.43) MAPTLMNASMN1; SMN2MEN1KMT2A
SCHEMBL31582669 0.82 MAPT (0.41) MAPTLMNASMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024074814-A1 COMPOSITION COMPRISING A FUNCTIONALISED DYE AND A DIALLYLAMINE COMONOMER AND USE SUBLINO LIMITED (GB) 2024-04-11 WO disclosed
EP-0863145-B1 Sunscreen compositions HOFFMANN LA ROCHE (CH) 2003-10-01 EP disclosed
US-5976512-A SUN SCREENING AGENTS. ROCHE VITAMINS INC. (US) 1999-11-02 US disclosed
EP-0863145-A2 Sunscreen compositions F. HOFFMANN-LA ROCHE AG (CH) 1998-09-09 EP disclosed