SCHEMBL7944222

SCHEMBL7944222

C=CCOc1ccc(-c2nc(-c3ccccc3)nc(-c3ccccc3)n2)c(O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.50
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
LMNA P02545 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
ALOX15 P16050 2/20 0.44
ADORA3 P0DMS8 1/20 0.44
TSHR P16473 1/20 0.44
ADORA2A P29274 1/20 0.44
ADORA2B P29275 1/20 0.44
ADORA1 P30542 1/20 0.44
FGFR1 P11362 1/20 0.42
NPSR1 Q6W5P4 4/20 0.42
KDM4E B2RXH2 2/20 0.42
MAPK1 P28482 2/20 0.42
USP2 O75604 1/20 0.42
TP53 P04637 1/20 0.42
POLB P06746 1/20 0.42
HSD17B10 Q99714 1/20 0.42
GAA P10253 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30887114 1.00 MAPT (0.50) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL31583281 0.97 MAPT (0.48) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL5584199 0.97 MAPT (0.48) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL7202492 0.90 MAPT (0.54) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL31583003 0.87 HPGD (0.53) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL30887140 0.87 MAPT (0.53) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL22558140 0.85 ALOX15 (0.48) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL30887170 0.84 LMNA (0.43) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL7942165 0.84 LMNA (0.43) MAPTMEN1KMT2ALMNASMN1; SMN2
SCHEMBL31582978 0.84 MAPT (0.43) MAPTMEN1KMT2ALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9020760-A None JP disclosed
EP-0750011-B1 Polysiloxanes as light stabilising agents CIBA SC HOLDING AG (CH) 2001-11-07 EP disclosed
US-5837792-A MODIFIED POLYSILOXANES WITH HYDROXYPHENYLDIARYL-S-TRIAZINE GROUPS FOR LIGHT, HEAT AND OXYGEN STABILIZATION CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-11-17 US disclosed
JP-H0920760-A TRIAZINE COMPOUND AND ULTRAVIOLET ABSORBER COMPOSED THEREOF ASAHI DENKA KOGYO KK 1997-01-21 JP disclosed
EP-0750011-A1 Polysiloxanes as light stabilising agents Ciba SC Holding AG (CH) 1996-12-27 EP disclosed