SCHEMBL5584199

SCHEMBL5584199

C=CCOc1ccc(-c2nc(-c3ccc(-c4ccccc4)cc3)nc(-c3ccc(-c4ccccc4)cc3)n2)c(O)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.48
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
LMNA P02545 2/20 0.44
ALOX15 P16050 2/20 0.43
ADORA3 P0DMS8 1/20 0.43
TSHR P16473 1/20 0.43
ADORA2A P29274 1/20 0.43
ADORA2B P29275 1/20 0.43
ADORA1 P30542 1/20 0.43
ALDH2 P05091 1/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41
NPSR1 Q6W5P4 3/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPK1 P28482 2/20 0.41
FGFR1 P11362 1/20 0.41
USP2 O75604 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31583281 1.00 MAPT (0.48) MAPTMEN1KMT2ASMN1; SMN2LMNA
SCHEMBL7944222 0.97 MAPT (0.50) MAPTMEN1KMT2ASMN1; SMN2LMNA
SCHEMBL30887114 0.97 MAPT (0.50) MAPTMEN1KMT2ASMN1; SMN2LMNA
SCHEMBL7202492 0.88 MAPT (0.54) MAPTMEN1KMT2ASMN1; SMN2LMNA
SCHEMBL30887140 0.87 MAPT (0.53) MAPTMEN1KMT2ASMN1; SMN2LMNA
SCHEMBL31583003 0.87 HPGD (0.53) MAPTMEN1KMT2ASMN1; SMN2LMNA
SCHEMBL13249565 0.85 ALOX15 (0.48) MAPTMEN1KMT2ASMN1; SMN2LMNA
SCHEMBL17357497 0.85 LMNA (0.41) MAPTMEN1KMT2ASMN1; SMN2LMNA
SCHEMBL31582978 0.84 MAPT (0.43) MAPTMEN1KMT2ASMN1; SMN2LMNA
SCHEMBL17993725 0.83 MAPT (0.47) MAPTMEN1KMT2ALMNAALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8986662-B2 Use of silane and siloxane bis(biphenyl) triazine derivatives as UV absorbers BASF SE (DE) 2015-03-24 US disclosed
US-8986662-B2 Use of silane and siloxane bis(biphenyl) triazine derivatives as UV absorbers BASF SE (DE) 2015-03-24 US disclosed
US-8585782-B2 Use of specific bis(biphenyl)triazine derivatives and mixtures thereof as UV absorbers BASF SE (DE) 2013-11-19 US disclosed
US-8585782-B2 Use of specific bis(biphenyl)triazine derivatives and mixtures thereof as UV absorbers BASF SE (DE) 2013-11-19 US disclosed
US-20130202542-A1 USE OF SILANE AND SILOXANE BIS(BIPHENYL) TRIAZINE DERIVATIVES AS UV ABSORBERS BASF SE (DE) 2013-08-08 US disclosed
US-20130202542-A1 USE OF SILANE AND SILOXANE BIS(BIPHENYL) TRIAZINE DERIVATIVES AS UV ABSORBERS BASF SE (DE) 2013-08-08 US disclosed
US-20130164231-A1 Use of specific bis(biphenyl)triazine derivatives and mixtures thereof as UV absorbers BASF SE (DE) 2013-06-27 US disclosed
US-20130164231-A1 Use of specific bis(biphenyl)triazine derivatives and mixtures thereof as UV absorbers BASF SE (DE) 2013-06-27 US disclosed
WO-2012052499-A1 USE OF SILANE AND SILOXANE BIS(BIPHENYL)TRIAZINE DERIVATIVES AS UV ABSORBERS BASF SE (DE) 2012-04-26 WO disclosed
WO-2012034932-A1 USE OF SPECIFIC BIS(BIPHENYL)TRIAZINE DERIVATIVES AND MIXTURES THEREOF AS UV ABSORBERS BASF SE (DE) 2012-03-22 WO disclosed
US-20090291289-A1 TRANSPARENT POLYMER ARTICLES OF LOW THICKNESS LEPPARD DAVID GEORGE 2009-11-26 US disclosed
US-20090291289-A1 TRANSPARENT POLYMER ARTICLES OF LOW THICKNESS LEPPARD DAVID GEORGE 2009-11-26 US disclosed
US-20090042006-A1 Transparent polymer articles of low thickness LEPPARD DAVID GEORGE 2009-02-12 US disclosed
US-20090042006-A1 Transparent polymer articles of low thickness LEPPARD DAVID GEORGE 2009-02-12 US disclosed
US-20070259165-A1 Transparent polymer articles of low thickness LEPPARD DAVID G 2007-11-08 US disclosed
US-20070259165-A1 Transparent polymer articles of low thickness LEPPARD DAVID G 2007-11-08 US disclosed
US-7265171-B2 Transparent polymer articles of low thickness CIBA SPECIALTY CHEMICALS CORP. (US) 2007-09-04 US disclosed
US-7265171-B2 Transparent polymer articles of low thickness CIBA SPECIALTY CHEMICALS CORP. (US) 2007-09-04 US disclosed
US-7166653-B2 Transparent polymer articles of low thickness CIBA SPECIALTY CHEMICALS CORP. (US) 2007-01-23 US disclosed
US-7166653-B2 Transparent polymer articles of low thickness CIBA SPECIALTY CHEMICALS CORP. (US) 2007-01-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130164231-A1 Use of specific bis(biphenyl)triazine derivatives and mixtures thereof as UV absorbers NR1H2, CBR3, NR1H3 MAPT 4821/4885MEN1 4239/4885KMT2A 3998/4885
US-20130202542-A1 USE OF SILANE AND SILOXANE BIS(BIPHENYL) TRIAZINE DERIVATIVES AS UV ABSORBERS CCNL2, MSR1, CYP2S1 MAPT 4472/4885MEN1 3254/4885KMT2A 1623/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.