Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892831 | 0.73 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL7155811 | 0.71 | ALDH1A1 (0.35) | HPGDALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7050212 | 0.69 | TDP1 (0.33) | GAAHPGDALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL7115387 | 0.67 | EPHX2 (0.36) | GAAEPHX1LMNAHPGDALDH1A1 | |
| SCHEMBL7112162 | 0.65 | TAAR1 (0.38) | L3MBTL1EPHX1LMNAALDH1A1CYP2C19 | |
| SCHEMBL29054020 | 0.64 | GAA (0.55) | GAAL3MBTL1EPHX1LMNAIDO1 | |
| SCHEMBL27821886 | 0.64 | GAA (0.55) | GAAL3MBTL1EPHX1LMNAIDO1 | |
| SCHEMBL4603729 | 0.64 | GAA (0.55) | GAAL3MBTL1EPHX1LMNAIDO1 | |
| SCHEMBL8910818 | 0.63 | POLB (0.31) | RAB9A | |
| SCHEMBL9501528 | 0.63 | ALDH1A1 (0.42) | GAAL3MBTL1EPHX1LMNAIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030220267-A1 | Borinic acid protease inhibitors | YALE UNIVERSITY | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220267-A1 | Borinic acid protease inhibitors | CMA1, CPA1, TPSAB1 | GAA 95/4885L3MBTL1 1988/4885EPHX1 654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.