Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.35 |
| ▸ | DDO | Q99489 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.34 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.34 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.34 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7199913 | 0.85 | GPR84 (0.36) | DAODDOMEN1KMT2AGRIN2D | |
| SCHEMBL5181580 | 0.73 | GPR84 (0.56) | DAOPKM | |
| SCHEMBL2551804 | 0.73 | MAPK1 (0.50) | MEN1KMT2AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL795980 | 0.72 | PDE3B (0.43) | DAODDOHPGD | |
| SCHEMBL794919 | 0.71 | PARP1 (0.31) | BRD4 | |
| SCHEMBL796757 | 0.70 | KMT2A (0.49) | DAOMEN1KMT2AKDM4EMAPT | |
| SCHEMBL5183717 | 0.69 | DAO (0.49) | DAOMEN1KMT2AKDM4EMAPT | |
| SCHEMBL5183774 | 0.68 | ESR1 (0.33) | KDM4EPKM | |
| SCHEMBL11468711 | 0.67 | SMN1; SMN2 (0.47) | MEN1KMT2AKDM4ESMN1; SMN2HTT | |
| SCHEMBL15514867 | 0.63 | HPGD (0.49) | MEN1KMT2AKDM4EUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003084538-A1 | METHODS FOR TREATING ROSACEA WITH PYRIDONES | MEDICIS PHARMACEUTICAL CORPORATION (US) | 2003-10-16 | — | — | WO | disclosed |