Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 13/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202712 | 0.93 | ALOX15 (0.50) | ALOX15MDM2ALDH1A1CYP1A2HPGD | |
| SCHEMBL6172472 | 0.91 | ALOX15 (0.51) | ALOX15MDM2 | |
| SCHEMBL7205430 | 0.87 | ALOX15 (0.53) | ALOX15MDM2ALDH1A1CYP1A2HPGD | |
| Water SCHEMBL27532088 | 0.86 | ALOX15 (0.52) | ALOX15MDM2ALDH1A1CYP1A2HPGD | |
| SCHEMBL7203970 | 0.84 | ALOX15 (0.53) | ALOX15 | |
| SCHEMBL6169599 | 0.84 | RECQL (0.44) | ALOX15MDM2HPGD | |
| SCHEMBL7202561 | 0.84 | ALOX15 (0.50) | ALOX15MDM2 | |
| SCHEMBL7203866 | 0.83 | ALOX15 (0.49) | ALOX15MDM2 | |
| SCHEMBL7202754 | 0.83 | ALOX15 (0.53) | ALOX15 | |
| SCHEMBL7206121 | 0.82 | ALOX15 (0.48) | ALOX15MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608070-B1 | Useful for treatment of medical condition in which prostaglandins are implicated as pathogens | NAKAO KAZUNARI (JP) | 2003-08-19 | — | — | US | disclosed |