Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | DDO | Q99489 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | STAT1 | P42224 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202599 | 0.85 | CYP1A2 (0.42) | CYP1A2CYP2C19DAODDOPDE3B | |
| SCHEMBL9846258 | 0.75 | TYMP (0.39) | CYP1A2CYP2C19PDE3BPDE3AHSD17B10 | |
| SCHEMBL7012269 | 0.72 | GRIN2D (0.48) | MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5188877 | 0.71 | CYP1A2 (0.60) | CYP1A2CYP2C19KDM4EALDH1A1HPGD | |
| SCHEMBL3794931 | 0.71 | KDM4E (0.64) | CYP1A2CYP2C19HSD17B10KDM4EALDH1A1 | |
| SCHEMBL9846189 | 0.69 | GRIN2D (0.45) | PDE3BPDE3AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL7202166 | 0.67 | CYP1A2 (0.42) | CYP1A2CYP2C19PDE3BPDE3AHSD17B10 | |
| SCHEMBL13569268 | 0.67 | EGFR (0.35) | CYP1A2CYP2C19HSD17B10KDM4EALDH1A1 | |
| SCHEMBL14423060 | 0.67 | TYMP (0.47) | CYP1A2CYP2C19PDE3BPDE3AHSD17B10 | |
| SCHEMBL891106 | 0.67 | NPSR1 (0.54) | CYP1A2CYP2C19HSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003084538-A1 | METHODS FOR TREATING ROSACEA WITH PYRIDONES | MEDICIS PHARMACEUTICAL CORPORATION (US) | 2003-10-16 | — | — | WO | disclosed |