Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | DDO | Q99489 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202591 | 0.85 | CYP1A2 (0.41) | CYP1A2CYP2C19PDE3BPDE3AMEN1 | |
| SCHEMBL12019527 | 0.72 | KDM4E (0.41) | PDE3BPDE3AKMT2AATMDAO | |
| SCHEMBL6060630 | 0.71 | HSD17B10 (0.47) | CYP1A2CYP2C19PDE3BPDE3AMEN1 | |
| SCHEMBL7012269 | 0.70 | GRIN2D (0.48) | MEN1KMT2APOLBMAPTGAA | |
| SCHEMBL5188877 | 0.69 | CYP1A2 (0.60) | CYP1A2CYP2C19CYP2C9POLBKDM5A | |
| SCHEMBL9846258 | 0.68 | TYMP (0.39) | CYP1A2CYP2C19PDE3BPDE3AMEN1 | |
| SCHEMBL3281983 | 0.68 | RAB9A (0.54) | CYP1A2CYP2C19CYP2C9POLBRAB9A | |
| SCHEMBL11647005 | 0.67 | HSD17B10 (0.43) | CYP1A2CYP2C19CYP2C9POLBRAB9A | |
| SCHEMBL14543745 | 0.65 | PDGFRB (0.44) | CYP1A2CYP2C19MEN1KMT2ACYP2C9 | |
| SCHEMBL25328180 | 0.65 | GABRA1 (0.33) | CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003084538-A1 | METHODS FOR TREATING ROSACEA WITH PYRIDONES | MEDICIS PHARMACEUTICAL CORPORATION (US) | 2003-10-16 | — | — | WO | disclosed |