Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 7/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7173202 | 0.79 | PGR (0.41) | PGRGAAMEN1KMT2A | |
| SCHEMBL3814920 | 0.73 | GRIN2D (0.40) | PGRGAAMEN1KMT2A | |
| SCHEMBL2719976 | 0.72 | CES1 (0.44) | CHEK1 | |
| SCHEMBL4752422 | 0.69 | CES1 (0.44) | CHEK1 | |
| SCHEMBL3817144 | 0.69 | CES1 (0.44) | CHEK1 | |
| SCHEMBL16574007 | 0.67 | ESR2 (0.52) | KCNA3GAAMGAMSIMGAM2 | |
| SCHEMBL278200 | 0.65 | ESR2 (0.49) | KCNA3GAAMGAMSIMGAM2 | |
| SCHEMBL321445 | 0.64 | CNR1 (0.53) | GAAMGAMSIMGAM2MEN1 | |
| SCHEMBL2717749 | 0.63 | CYP3A4 (0.37) | GAA | |
| SCHEMBL10859508 | 0.63 | EGFR (0.45) | PGRGAAMEN1KMT2ACHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003517459-A | — | — | 2003-05-27 | — | — | JP | claimed |
| JP-2002543159-A | — | — | 2002-12-17 | — | — | JP | claimed |
| EP-1173213-A1 | COMPOSITIONS CONTAINING BENZIMIDAZOLONES AND PROGESTOGENS | American Home Products Corporation (US) | 2002-01-23 | — | — | EP | claimed |
| EP-1173423-A1 | BENZIMIDAZOLONES AND ANALOGUES AND THEIR USE AS PROGESTERONE RECEPTOR LIGANDS | American Home Products Corporation (US) | 2002-01-23 | — | — | EP | claimed |
| WO-2000066564-A1 | BENZIMIDAZOLONES AND ANALOGUES AND THEIR USE AS PROGESTERONE RECEPTOR LIGANDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-11-09 | — | — | WO | claimed |
| WO-2000066168-A1 | COMPOSITIONS CONTAINING BENZIMIDAZOLONES AND PROGESTOGENS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-11-09 | — | — | WO | claimed |