Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7206016 | 0.86 | — | — | |
| SCHEMBL8319931 | 0.76 | — | — | |
| SCHEMBL5702835 | 0.71 | GPR3 (0.34) | — | |
| SCHEMBL7202636 | 0.68 | — | — | |
| SCHEMBL8535341 | 0.65 | GPR3 (0.34) | — | |
| SCHEMBL8861776 | 0.62 | HTR2A (0.37) | — | |
| SCHEMBL5702797 | 0.57 | GPR3 (0.33) | — | |
| SCHEMBL6402510 | 0.57 | BCHE (0.37) | — | |
| SCHEMBL6401822 | 0.57 | PTPN1 (0.41) | — | |
| SCHEMBL6402365 | 0.57 | PTPN1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0849273-B1 | Metallocenes, their preparation and use in the polymerization of alpha-olefins | POLIMERI EUROPA SPA (IT) | 2003-05-02 | — | — | EP | disclosed |
| US-5948873-A | COORDINATION CATALYST | ENICHEM S.P.A. (IT) | 1999-09-07 | — | — | US | disclosed |
| EP-0849273-A1 | Metallocenes, their preparation and use in the polymerization of alpha-olefins | ENICHEM S.p.A. (IT) | 1998-06-24 | — | — | EP | disclosed |