Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 6/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.34 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6346285 | 0.89 | CYP2C19 (0.46) | PPARAPPARGCYP2C19L3MBTL1LMNA | |
| SCHEMBL7202669 | 0.84 | PTGER1 (0.43) | PPARAPPARGCYP2C19LMNAALDH1A1 | |
| SCHEMBL6344402 | 0.80 | ALDH1A1 (0.49) | L3MBTL1MEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL6345166 | 0.77 | ALDH1A1 (0.46) | L3MBTL1MEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL6342853 | 0.72 | ALDH1A1 (0.46) | L3MBTL1MEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL6346577 | 0.72 | ELANE (0.44) | PPARAPPARGCYP2C19L3MBTL1MEN1 | |
| SCHEMBL25576433 | 0.71 | ALDH1A1 (0.51) | L3MBTL1MEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL10264120 | 0.71 | RIPK1 (0.50) | L3MBTL1MEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL10264364 | 0.71 | ALDH1A1 (0.47) | L3MBTL1MEN1LMNAKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL25212066 | 0.70 | ALDH1A1 (0.50) | L3MBTL1MEN1LMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002030882-A9 | SULFOXIDE AND BIS-SULFOXIDE COMPOUNDS AND COMPOSITIONS FOR CHOLESTEROL MANAGEMENT AND RELATED USES | ESPERION THERAPEUTICS INC (US) | 2003-02-20 | — | — | WO | disclosed |