Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | IDH1 | O75874 | 7/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7202710 | 1.00 | ALDH1A1 (0.42) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL7204889 | 1.00 | ALDH1A1 (0.42) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL21447473 | 0.87 | LMNA (0.39) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL21447256 | 0.87 | LMNA (0.39) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL21447258 | 0.87 | LMNA (0.39) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL23357302 | 0.87 | LMNA (0.39) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL23357120 | 0.87 | LMNA (0.39) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL23356926 | 0.87 | LMNA (0.39) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL21447259 | 0.87 | LMNA (0.39) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL23375810 | 0.87 | LMNA (0.39) | ALDH1A1GAAHTTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003043996-A1 | A METHOD FOR PREPARING OF CHIRAL 2,2-DIMETHYLCYCLOPROPANECARBOXYL DERIVATIVES | CHEMTECH RESEARCH INCORPORATION (KR) | 2003-05-30 | — | — | WO | disclosed |