Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 3/20 | 0.37 |
| ▸ | RXRB | P28702 | 3/20 | 0.37 |
| ▸ | RXRG | P48443 | 3/20 | 0.37 |
| ▸ | RARB | P10826 | 2/20 | 0.37 |
| ▸ | RARG | P13631 | 2/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2406553 | 0.89 | HCAR2 (0.46) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL2406424 | 0.81 | HCAR2 (0.53) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL2897171 | 0.77 | HCAR2 (0.33) | HCAR2RORC | |
| SCHEMBL17178097 | 0.71 | — | — | |
| SCHEMBL16794314 | 0.69 | SMN1; SMN2 (0.43) | HCAR2 | |
| SCHEMBL30908520 | 0.68 | HCAR2 (0.43) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL16703224 | 0.68 | HCAR2 (0.50) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL13341431 | 0.67 | CDC7 (0.36) | HCAR2 | |
| SCHEMBL28045873 | 0.66 | HCAR2 (0.52) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL23146241 | 0.65 | HCAR2 (0.47) | RXRARXRBRXRGRARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003076440-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS CALCITONIN AGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-09-18 | — | — | WO | disclosed |