Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7567111 | 0.92 | ADORA3 (0.44) | ADORA2AADORA2BADORA3ADORA1 | |
| Formic Acid SCHEMBL7202947 | 0.92 | ADORA3 (0.47) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL7203734 | 0.91 | ADORA3 (0.50) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL7566399 | 0.88 | ADORA2A (0.41) | ADORA2AADORA2BADORA1 | |
| SCHEMBL7230919 | 0.84 | ADORA2A (0.47) | ADORA2AADORA2BADORA3ADORA1 | |
| Formic Acid SCHEMBL7567103 | 0.83 | ADORA3 (0.48) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL7207501 | 0.82 | ADORA3 (0.51) | ADORA2AADORA2BADORA3ADORA1 | |
| Formic Acid SCHEMBL7566394 | 0.79 | ADORA2A (0.45) | ADORA2AADORA2BADORA1 | |
| SCHEMBL7207963 | 0.78 | ADORA2A (0.44) | ADORA2AADORA2BADORA1 | |
| SCHEMBL7221852 | 0.77 | ADORA2A (0.38) | ADORA2AADORA2BADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610665-B1 | Treatment of inflammatory diseases, asthma or chronic obstructive pulmonary disease | SMITHKLINE BEECHAM CORPORATION | 2003-08-26 | — | — | US | disclosed |
| EP-1056759-B1 | 2-(PURIN-9-YL) -TETRAHYDROFURAN-3, 4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-09-04 | — | — | EP | disclosed |