Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 7/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 9/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207501 | 0.96 | ADORA3 (0.51) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL7567111 | 0.92 | ADORA3 (0.44) | ADORA3ADORA1ADORA2AADORA2B | |
| Formic Acid SCHEMBL7202947 | 0.91 | ADORA3 (0.47) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL7203734 | 0.88 | ADORA3 (0.50) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL7202955 | 0.83 | ADORA2A (0.43) | ADORA3ADORA1ADORA2AADORA2B | |
| Formic Acid SCHEMBL7230913 | 0.82 | ADORA3 (0.54) | ADORA3ADORA1ADORA2AADORA2B | |
| Formic Acid SCHEMBL7566394 | 0.80 | ADORA2A (0.45) | ADORA1ADORA2AADORA2B | |
| SCHEMBL1982965 | 0.78 | ADORA3 (0.72) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL7012704 | 0.78 | ADORA3 (0.72) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL7456601 | 0.78 | ADORA3 (0.58) | ADORA3ADORA1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056759-B1 | 2-(PURIN-9-YL) -TETRAHYDROFURAN-3, 4-DIOL DERIVATIVES | GLAXO GROUP LTD (GB) | 2002-09-04 | — | — | EP | disclosed |