Ethylene Glycol

Ethylene Glycol

SCHEMBL7203024

Cc1cc(Cl)c(C)cc1Cl.OCCO

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.48
LMNA P02545 1/20 0.43
GRIN2D O15399 1/20 0.39
GRIN3B O60391 1/20 0.39
GRIN1 Q05586 1/20 0.39
GRIN2A Q12879 1/20 0.39
GRIN2B Q13224 1/20 0.39
GRIN2C Q14957 1/20 0.39
GRIN3A Q8TCU5 1/20 0.39
SIRT1 Q96EB6 1/20 0.39
CYP3A4 P08684 2/20 0.39
CHRM1 P11229 1/20 0.38
ALOX15 P16050 1/20 0.38
MAOA P21397 1/20 0.38
TBXA2R P21731 1/20 0.38
ADRA1A P35348 1/20 0.38
HTR2B P41595 1/20 0.38
ALDH1A1 P00352 2/20 0.36
GAA P10253 2/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL120848 0.84 CD44 (0.61) CD44LMNAGRIN2DGRIN3BGRIN1
Water SCHEMBL29026586 0.81 CD44 (0.58) CD44LMNAGRIN2DGRIN3BGRIN1
SCHEMBL13696619 0.79 SHBG (0.42) CD44LMNAGRIN2DGRIN3BGRIN1
SCHEMBL2219302 0.78 CD44 (0.55) CD44LMNAGRIN2DGRIN3BGRIN1
SCHEMBL168826 0.78 CD44 (0.55) CD44LMNAGRIN2DGRIN3BGRIN1
SCHEMBL13696620 0.76 CD44 (0.42) CD44LMNAGRIN2DGRIN3BGRIN1
SCHEMBL8459523 0.74 TSHR (0.60) CD44LMNAGRIN2DGRIN3BGRIN1
SCHEMBL4062679 0.74 LMNA (0.58) CD44LMNAGRIN2DGRIN3BGRIN1
SCHEMBL3483821 0.74 CD44 (0.46) CD44LMNAGRIN2DGRIN3BGRIN1
SCHEMBL17466157 0.74 CD44 (0.41) CD44LMNAGRIN2DGRIN3BGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6409949-B1 FEED RESIN CONTAINING CHAIN EXTENSION AGENT IS SUBJECTED TO MIXING WHILE BEING DEAERATED UNDER REDUCED PRESSURE IN SINGLE THICKENING CHAMBER KABUSHIKI KAISHA KOBE SEIKO SHO (KOBE STEEL, LTD.) (JP) 2002-06-25 US claimed
US-6604848-B2 Drying, dehydrating, and dearating under low pressure KABUSHIKI KAISHA KOBE SEIKO SHO (JP) 2003-08-12 US disclosed
US-20020141282-A1 Method and apparatus for kneading polyester resins continuously KABUSHIKI KAISHA KOBE SEIKO SHO (KOBE STEEL, LTD.) (JP) 2002-10-03 US disclosed
US-6409949-B1 FEED RESIN CONTAINING CHAIN EXTENSION AGENT IS SUBJECTED TO MIXING WHILE BEING DEAERATED UNDER REDUCED PRESSURE IN SINGLE THICKENING CHAMBER KABUSHIKI KAISHA KOBE SEIKO SHO (KOBE STEEL, LTD.) (JP) 2002-06-25 US disclosed