Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | EBP | Q15125 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27796449 | 0.79 | SIGMAR1 (0.41) | SIGMAR1GAAMEN1KMT2ACHRM2 | |
| SCHEMBL720308 | 0.79 | CNR1 (0.36) | SIGMAR1GAASCN5ASCN9AMEN1 | |
| SCHEMBL3972776 | 0.78 | SIGMAR1 (0.37) | SIGMAR1GAASCN5ASCN9AMEN1 | |
| SCHEMBL6755985 | 0.77 | LTA4H (0.37) | SIGMAR1GAAMEN1KMT2ACNR1 | |
| SCHEMBL9782412 | 0.77 | SIGMAR1 (0.46) | SIGMAR1GAASCN5ASCN9AMEN1 | |
| SCHEMBL5395161 | 0.77 | SIGMAR1 (0.64) | SIGMAR1GAASCN5ASCN9ACHRM2 | |
| SCHEMBL3809940 | 0.77 | SIGMAR1 (0.46) | SIGMAR1GAASCN5ASCN9AMEN1 | |
| SCHEMBL6471777 | 0.77 | SIGMAR1 (0.46) | SIGMAR1GAASCN5ASCN9AMEN1 | |
| SCHEMBL3422456 | 0.77 | SIGMAR1 (0.46) | SIGMAR1GAASCN5ASCN9AMEN1 | |
| SCHEMBL11413546 | 0.77 | SIGMAR1 (0.64) | SIGMAR1GAASCN5ASCN9ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2438166-B1 | METHOD FOR PREPARING PROTEIN, DNA, AND RNA FROM CELL | CANON KK (JP) | 2015-11-11 | — | — | EP | disclosed |
| US-9169480-B2 | Method for preparing protein, DNA, and RNA from cell | CANON KABUSHIKI KAISHA (JP) | 2015-10-27 | — | — | US | disclosed |
| EP-2438166-A1 | METHOD FOR PREPARING PROTEIN, DNA, AND RNA FROM CELL | Canon Kabushiki Kaisha (JP) | 2012-04-11 | — | — | EP | disclosed |
| US-20120053329-A1 | METHOD FOR PREPARING PROTEIN, DNA, AND RNA FROM CELL | CANON KABUSHIKI KAISHA (JP) | 2012-03-01 | — | — | US | disclosed |
| WO-2010140598-A1 | METHOD FOR PREPARING PROTEIN, DNA, AND RNA FROM CELL | CANON KABUSHIKI KAISHA (JP) | 2010-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053329-A1 | METHOD FOR PREPARING PROTEIN, DNA, AND RNA FROM CELL | DDX21, HNRNPR, NXF1 | SIGMAR1 3744/4885GAA 3467/4885SCN5A 3273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.