Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 13/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6169395 | 0.88 | PTGS2 (0.53) | PTGS2PTGS1MEN1GAAMAPT | |
| SCHEMBL6169728 | 0.82 | PTGS2 (0.84) | PTGS2PTGS1KDM4EMEN1ALDH1A1 | |
| SCHEMBL28744503 | 0.77 | PTGS1 (0.45) | PTGS2PTGS1KDM4EMEN1ALDH1A1 | |
| SCHEMBL6169798 | 0.76 | PTGS2 (0.51) | PTGS2PTGS1KDM4EALDH1A1GAA | |
| SCHEMBL6169641 | 0.75 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL6170649 | 0.75 | PTGS2 (0.51) | PTGS2PTGS1KDM4EMEN1ALDH1A1 | |
| SCHEMBL6169251 | 0.74 | PTGS2 (1.00) | PTGS2PTGS1KDM4EMEN1ALDH1A1 | |
| SCHEMBL9449371 | 0.73 | KDM4E (0.56) | PTGS2PTGS1KDM4EMAPT | |
| SCHEMBL11331485 | 0.72 | KDM4E (0.63) | PTGS2PTGS1KDM4EMEN1ALDH1A1 | |
| SCHEMBL6171850 | 0.72 | PTGS2 (0.61) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6608070-B1 | Useful for treatment of medical condition in which prostaglandins are implicated as pathogens | NAKAO KAZUNARI (JP) | 2003-08-19 | — | — | US | disclosed |