SCHEMBL7203201

SCHEMBL7203201

CC(CNC[C@H](O)c1cc(F)c(N)c(Br)c1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 12/20 0.47
KDM4E B2RXH2 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
PDPK1 O15530 1/20 0.41
AOC3 Q16853 3/20 0.40
ADRB1 P08588 1/20 0.37
ADRB3 P13945 1/20 0.37
ALDH1A1 P00352 2/20 0.37
TAAR1 Q96RJ0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7147981 0.79 ADRB2 (0.60) ADRB2ADRB1ADRB3
SCHEMBL7147978 0.79 ADRB2 (0.60) ADRB2ADRB1ADRB3
SCHEMBL11023770 0.78 ADRB2 (0.61) ADRB2KDM4EADRB1ADRB3ALDH1A1
SCHEMBL8976776 0.77 KDM4E (0.77) ADRB2KDM4EL3MBTL1AOC3ALDH1A1
SCHEMBL9061582 0.77 KDM4E (0.77) ADRB2KDM4EL3MBTL1AOC3ALDH1A1
Hydrochloric Acid SCHEMBL11036484 0.77 ADRB2 (0.60) ADRB2KDM4EADRB1ADRB3
SCHEMBL11030043 0.74 ADRB2 (0.58) ADRB2KDM4EADRB1
Hydrochloric Acid SCHEMBL10887060 0.73 ADRB2 (0.60) ADRB2KDM4EADRB1
SCHEMBL11642333 0.71 ADRB2 (0.51) ADRB2KDM4EADRB1ADRB3
SCHEMBL7153101 0.71 ADRB2 (0.51) ADRB2KDM4EL3MBTL1ADRB1ADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0924194-B1 Processes for producing optically active 2-amino-1-phenylethanol derivatives DAICEL CHEM (JP) 2003-05-14 EP disclosed