Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | AOC3 | Q16853 | 4/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9061582 | 1.00 | KDM4E (0.77) | KDM4EL3MBTL1ALDH1A1AOC3TAAR1 | |
| SCHEMBL11046082 | 0.88 | TAAR1 (0.68) | KDM4EL3MBTL1AOC3TAAR1KMT2A | |
| SCHEMBL4408535 | 0.88 | KDM4E (1.00) | KDM4EL3MBTL1ALDH1A1AOC3KMT2A | |
| SCHEMBL7532494 | 0.88 | KDM4E (1.00) | KDM4EL3MBTL1ALDH1A1AOC3KMT2A | |
| SCHEMBL11459286 | 0.87 | KDM4E (0.59) | KDM4EL3MBTL1ALDH1A1TAAR1KMT2A | |
| SCHEMBL12186411 | 0.86 | KDM4E (0.80) | KDM4EL3MBTL1ALDH1A1AOC3KMT2A | |
| SCHEMBL7114926 | 0.86 | KDM4E (0.80) | KDM4EL3MBTL1ALDH1A1AOC3KMT2A | |
| SCHEMBL9799340 | 0.85 | ALDH1A1 (0.56) | KDM4EL3MBTL1ALDH1A1TAAR1KMT2A | |
| SCHEMBL11228161 | 0.83 | KDM4E (0.74) | KDM4EL3MBTL1ALDH1A1AOC3KMT2A | |
| SCHEMBL15355176 | 0.83 | KDM4E (0.74) | KDM4EL3MBTL1ALDH1A1AOC3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508461-A | ANTIOBESITY AGENTS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-04-16 | — | — | US | disclosed |