Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7203266 | 1.00 | BRD4 (0.31) | BRD4 | |
| SCHEMBL7203263 | 1.00 | BRD4 (0.31) | BRD4 | |
| SCHEMBL8946965 | 0.72 | TP53 (0.33) | BRD4 | |
| SCHEMBL8946474 | 0.70 | — | — | |
| SCHEMBL8946467 | 0.70 | — | — | |
| SCHEMBL8946470 | 0.70 | — | — | |
| SCHEMBL8946458 | 0.68 | ADRA2A (0.37) | — | |
| SCHEMBL8946453 | 0.68 | ADRA2A (0.37) | — | |
| SCHEMBL8946404 | 0.68 | ADRA2A (0.37) | — | |
| SCHEMBL8946532 | 0.67 | CYP1A2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | claimed |
| EP-0481708-A1 | Indenoindole compounds | UNIVERSITY OF BATH (GB) | 1992-04-22 | — | — | EP | claimed |
| US-6602511-B2 | Lecithin, sphingolipid or galacto lipid hydrophobic surfactant and hydrophilic surfactant; oil in water emulsion; administering low water soluble drugs | ASTRAZENECA AB (SE) | 2003-08-05 | — | — | US | disclosed |
| EP-0850046-B1 | MICROEMULSIONS FOR USE AS VEHICLES FOR ADMINISTRATION OF ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2002-12-04 | — | — | EP | disclosed |
| US-20010007663-A1 | MICROEMULSIONS FOR USE AS VEHICLES FOR ADMINISTRATION OF ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2001-07-12 | — | — | US | disclosed |
| EP-0850046-A2 | MICROEMULSIONS FOR USE AS VEHICLES FOR ADMINISTRATION OF ACTIVE COMPOUNDS | Astra Aktiebolag (SE) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997009964-A1 | MICROEMULSIONS FOR USE AS VEHICLES FOR ADMINISTRATION OF ACTIVE COMPOUNDS | ASTRA AKTIEBOLAG (SE) | 1997-03-20 | — | — | WO | disclosed |
| US-5516788-A | TREATMENT OF ATHEROSCLEROSIS; ANTIISCHEMIC, ANTICARCINOGENIC AGENTS; ANTICOAGULANTS | UNIVERSITY OF BATH (GB) | 1996-05-14 | — | — | US | disclosed |
| WO-1992006956-A1 | INDENOINDOLE COMPOUNDS | UNIVERSITY OF BATH (GB) | 1992-04-30 | — | — | WO | disclosed |
| EP-0481708-A1 | Indenoindole compounds | UNIVERSITY OF BATH (GB) | 1992-04-22 | — | — | EP | disclosed |