Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | EYA2 | O00167 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7762673 | 0.96 | TDP1 (0.40) | TDP1TSHRKDM4ELMNACHRM2 | |
| SCHEMBL6859731 | 0.93 | TDP1 (0.47) | TDP1TSHRKDM4ELMNACHRM2 | |
| SCHEMBL17177620 | 0.87 | TSHR (0.32) | TDP1TSHRKDM4ELMNACHRM2 | |
| SCHEMBL18362360 | 0.86 | KMT2A (0.47) | TDP1TSHRKDM4ELMNAMEN1 | |
| SCHEMBL438113 | 0.84 | TDP1 (0.58) | TDP1TSHRKDM4ELMNACHRM2 | |
| SCHEMBL4621864 | 0.84 | TDP1 (0.58) | TDP1TSHRKDM4ELMNACHRM2 | |
| SCHEMBL992084 | 0.84 | TDP1 (0.58) | TDP1TSHRKDM4ELMNACHRM2 | |
| SCHEMBL19458 | 0.83 | TDP1 (0.42) | TDP1TSHRKDM4ELMNACHRM2 | |
| SCHEMBL18429454 | 0.83 | GAA (0.44) | TDP1KDM4EMEN1KMT2ACA12 | |
| SCHEMBL3661157 | 0.83 | STING1 (0.31) | NR1D1NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6607710-B1 | Provide a bisphosphonic acid derivative and said bisphosphonic acid derivative being labeled with a radioactive nuclide, which has properties of rapid accumulation to the bone and rapid urinary excretion. | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2003-08-19 | — | — | US | disclosed |