Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | GAA | P10253 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6734735 | 0.95 | MAPT (0.41) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL6738481 | 0.87 | MAPT (0.36) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL6267263 | 0.78 | ALDH1A1 (0.44) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL6739710 | 0.78 | CYP3A4 (0.34) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL6740519 | 0.78 | ADRA2B (0.31) | — | |
| SCHEMBL6739385 | 0.78 | NTRK1 (0.36) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL6272864 | 0.77 | ALDH1A1 (0.48) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL6270613 | 0.77 | ALDH1A1 (0.42) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL6273914 | 0.76 | MAPT (0.57) | ALDH1A1GAAMAPTKDM4EMEN1 | |
| SCHEMBL6738414 | 0.76 | ADRA2B (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602302-B1 | Mixtures of carbocyclic amines such as 2-((2-aminophenylamino) -methyl)-1,4-diaminobenzene, couplers and developers, having photostability, wash and colorfastness, used for dyeing human hair | WELLA AG (DE) | 2003-08-05 | — | — | US | claimed |