SCHEMBL7203582

SCHEMBL7203582

C=CCc1ccccc1C(C=C)(c1ccccc1O)c1ccccc1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.43
GABRB2 P47870 4/20 0.43
AKR1B1 P15121 2/20 0.38
ALDH1A1 P00352 3/20 0.37
TSHR P16473 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
MEN1 O00255 4/20 0.35
MAPT P10636 4/20 0.35
KMT2A Q03164 4/20 0.35
GAA P10253 4/20 0.35
KDM4E B2RXH2 3/20 0.35
HSPA5 P11021 1/20 0.35
CASP1 P29466 1/20 0.35
HSD17B10 Q99714 1/20 0.35
POLB P06746 2/20 0.35
ACHE P22303 2/20 0.33
XDH P47989 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MAPK1 P28482 1/20 0.33
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21647329 0.80 GABRA1 (0.49) GABRA1GABRB2AKR1B1ALDH1A1MEN1
2-Allylphenol SCHEMBL10901820 0.77 TSHR (0.60) GABRA1GABRB2AKR1B1ALDH1A1TSHR
2-Allylphenol SCHEMBL565880 0.76 GABRA1 (0.53) GABRA1GABRB2AKR1B1ALDH1A1TSHR
2-Allylphenol SCHEMBL160157 0.76 GABRA1 (0.57) GABRA1GABRB2AKR1B1TSHRMEN1
2-Allylphenol SCHEMBL31591833 0.76 GABRA1 (0.57) GABRA1GABRB2AKR1B1TSHRMEN1
2-Allylphenol SCHEMBL5489147 0.76 GABRA1 (0.57) GABRA1GABRB2AKR1B1TSHRMEN1
2-Allylphenol SCHEMBL29381085 0.76 GABRA1 (0.57) GABRA1GABRB2AKR1B1TSHRMEN1
SCHEMBL5408655 0.74 ALDH1A1 (0.45) ALDH1A1TSHRTDP1MAPTKDM4E
SCHEMBL9617369 0.74 IDO1 (0.33) ALDH1A1TSHRTDP1HSPA5
2-Allylphenol SCHEMBL3877760 0.74 GABRA1 (0.55) GABRA1GABRB2AKR1B1TSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6649674-B2 Molding materials BAYER AKTIENGESELLSCHAFT (DE) 2003-11-18 US disclosed
US-20030018108-A1 Flame-proof polyester molding compositions comprising hydrotalcite, red phosphorus and melamine cyanurate LANXESS DEUTSCHLAND GMBH (DE) 2003-01-23 US disclosed
US-6423767-B1 SHAPED ARTICLES, FILMS OR FIBERS, EXTERNAL AUTOBODY PARTS BASF AKTIENGESELLSCHAFT (DE) 2002-07-23 US disclosed