Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 2/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11632216 | 0.89 | RAB9A (0.62) | RAB9ARXFP1KMT2AMAPTALDH1A1 | |
| SCHEMBL3719794 | 0.87 | MAOB (0.63) | RAB9ARXFP1KMT2AMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL11632213 | 0.87 | RAB9A (0.61) | RAB9ARXFP1KMT2AMAPTALDH1A1 | |
| SCHEMBL1493670 | 0.87 | KMT2A (0.60) | RAB9ARXFP1KMT2AMAPTALDH1A1 | |
| SCHEMBL3276281 | 0.87 | RAB9A (0.57) | RAB9ARXFP1KMT2AMAPTALDH1A1 | |
| SCHEMBL11302977 | 0.87 | RAB9A (0.49) | RAB9ARXFP1KMT2AMAPTALDH1A1 | |
| SCHEMBL28145792 | 0.84 | RAB9A (0.62) | RAB9ARXFP1KMT2AMAPTALDH1A1 | |
| SCHEMBL11028508 | 0.83 | MAPT (0.61) | RAB9ARXFP1KMT2AMAPTALDH1A1 | |
| SCHEMBL19165746 | 0.83 | MAOB (0.59) | RAB9ARXFP1KMT2AMAPTALDH1A1 | |
| SCHEMBL6388462 | 0.83 | RAB9A (0.57) | RAB9ARXFP1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1324006-C | Beta-amino acid nitrile derivs. | HOFFMANN LA ROCHE (CH) | 2007-07-04 | — | — | CN | disclosed |
| US-6632606-B1 | Methods for single nucleotide polymorphism detection | ACLARA BIOSCIENCES, INC. | 2003-10-14 | — | — | US | disclosed |
| CN-1436168-A | Beta-amino acid nitrile derivs. | HOFFMANN LA ROCHE (CH) | 2003-08-13 | — | — | CN | disclosed |
| WO-2000056925-A2 | METHODS FOR SINGLE NUCLEOTIDE POLYMORPHISM DETECTION | ACLARA BIOSCIENCES, INC. (US) | 2000-09-28 | — | — | WO | disclosed |
| US-5721099-A | Complex combinatorial chemical libraries encoded with tags | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1998-02-24 | — | — | US | disclosed |
| US-5565324-A | FOR IDENTIFICATION OF NON-OLIGOMERIC COMPOUND, USING SOLID SUPPORT | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1996-10-15 | — | — | US | disclosed |